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The Park Lab

Single-cell Systems Biology in Development & Disease

The Park Lab is affiliated with the Chemical & Biomolecular Engineering Department, as part of the School of Science and Engineering at Tulane University. We investigate molecular mechanisms underlying cell plasticity and tumor cell heterogeneity at the single-cell level in the context of drug treatment, cell-to-cell interactions, and cell dynamics. We are interested in developing omics-scale models of gene regulatory networks to understand and predict complex molecular behavior in development and disease.

We are an interdisciplinary team drawing on tools and approaches from engineering, computational and experimental biology, cancer biology, and bioinformatics. We apply a range of experimental, computational, and theoretical frameworks to infer and test gene regulatory network mechanisms driving the dynamics of cell populations. Ultimately, our goals are to elucidate underlying principles of cell plasticity and identify novel strategies to overcome therapy resistance in cancers like glioblastoma.

Research Interests

Systems biology, single-cell analytics, statistical & mathematical modeling, dynamics, cell plasticity, drug resistance, cancer stem cells, tumor microenvironment, biological controls

Park Research Lab

330 Lindy Claiborne Boggs Center for Energy and Biotechnology

6823 St. Charles Ave.

New Orleans, LA 70118

© Park Research Lab 2026

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